The short version
- Colorado issued its first healing center license on March 31, 2025.
- By early 2026, 34 healing centers were licensed, with more applications pending.
- Some centers charge about $3,500 for a full program of preparation, session, and integration.
- A 2026 law added liability protections for facilitators and created an ibogaine research pilot.
From vote to first license
Colorado voters approved Proposition 122, the Natural Medicine Health Act, in 2022. It took until March 31, 2025, for the state's Natural Medicine Division to issue the first healing center license, to The Center Origin in Denver. Even then, the center couldn't open until local approvals, a licensed cultivator, and a licensed testing lab were all in place.1 Building a supply chain from nothing takes a while.
How fast it's grown
By early 2026, Colorado had 34 licensed healing centers, with more than a dozen more applications pending.2 Licenses come in two sizes. Standard healing centers can store larger quantities of psilocybin, while micro healing centers, the more common type, are capped at a smaller amount and are often run inside existing therapy practices, wellness studios, or clinics.23
Centers are spread well beyond Denver and Boulder, including Aspen, Fort Collins, Salida, Manitou Springs, and Montrose. The state maintains a directory built with healing center owners, and a separate tool for verifying facilitator licenses.5
What it costs
Cost remains the biggest complaint. Colorado Public Radio found two centers charging about $3,500 for a full program covering screening, preparation, the psilocybin session, and integration, while another priced sessions depending on services and add-ons. Operators said build-out costs alone can run around $25,000, which pushes prices up.2 Insurance doesn't cover any of it.
What a session looks like
The structure will feel familiar if you've read about Oregon. Clients go through medical screening and a medication review, then usually two preparation meetings with their facilitator. The psilocybin session takes place in a prepared room with beds or reclining chairs, eye masks, and music, with a facilitator present. Integration sessions follow.2 Read more in what psilocybin therapy is like.
What changed in 2026
Governor Jared Polis signed House Bill 26-1325 in June 2026, and it took effect August 12. It gives facilitators liability protection for natural medicine services except in cases of intentional misconduct or gross negligence, updates facilitator licensing and enforcement, and creates an ibogaine research pilot program at up to five sites.4
How Colorado differs from Oregon
| Colorado | Oregon | |
|---|---|---|
| Personal possession and growing | Legal for adults 21+, no sales | Illegal outside licensed centers |
| Substances | Psilocybin now; law allows others like DMT and mescaline (excluding peyote) later | Psilocybin only |
| Center sizes | Standard and micro licenses | Single service center license |
| First licensed center | March 2025 | 2023 |
Find a Colorado healing center
Our psilocybin therapist finder lists licensed Colorado healing centers across the state, with links to the official directories so you can verify licenses before you book.
Sources
- Colorado Natural Medicine Division. The DOR's Natural Medicine Division issues Colorado's first healing center license. 2025. nmd.colorado.gov
- Colorado Public Radio. We toured three psychedelic healing centers in Colorado. Here's what we saw. February 4, 2026. cpr.org
- Colorado Natural Medicine Division. Healing centers. nmd.colorado.gov
- Unlimited Sciences. Psychedelic policy is changing across the U.S.: what states are doing in 2026. unlimitedsciences.org
- Colorado Natural Medicine Division. Accessing regulated natural medicine. nmd.colorado.gov
This article is for education only and is not medical or legal advice. Psilocybin is a Schedule I substance under U.S. federal law. Talk with a licensed clinician before making decisions about your health. In a crisis, call or text 988.